CARDINAL HEALTH CLASSIC ELECTRODES
From: $4.91
Incorporates a silver ink/carbon film conductive layer, proven to efficiently disperse electrical current over the entire surface of the electrode. Features an intuitive life tab for easy removal of the electrode after application. The hydrogel is formulated with pure aloe vera, known for its hydrating properties and natural moisturizing effects. A tinted double-coated liner makes storage easy as electrodes can be returned to either side. Multiple applications from 10-15 days.
All Variations
| SKU | Stock | Size | Shape | Sterility | Packaging | Price | Quantity | Price Per | Add to Cart |
|---|---|---|---|---|---|---|---|---|---|
| SKU: CA-EP84159 | Stock: In Stock | Size: 2x2 | Shape: Square | Sterility: | Packaging: 4 electrodes per pack (4 electrodes total) | Price: $4.97 | Price Per: pack | ||
| SKU: CA-EP84169 | Stock: In Stock | Size: 4x2 | Shape: Rectangle | Sterility: | Packaging: 4 electrodes per pack (4 electrodes total) | Price: $7.46 | variation_pricing_suffix: pack | ||
| SKU: CA-EP84149 | Stock: In Stock | Size: 2 | Shape: Round | Sterility: | Packaging: 4 electrodes per pack (4 electrodes total) | Price: $4.91 | variation_pricing_suffix: pack | ||
| SKU: CA-EP84599 | Stock: In Stock | Size: 2x4 | Shape: Oval | Sterility: | Packaging: 1 pack per case (1 pack total) | Price: $7.50 | variation_pricing_suffix: case | ||
| SKU: CA-ES82260 | Stock: In Stock | Size: 1.6x1.75 | Shape: | Sterility: Non-Sterile | Packaging: 40 electrodes per pack, 10 packs per case (400 electrodes total) | Price: $424.62 | variation_pricing_suffix: case | ||
| SKU: CA-EP85159 | Stock: In Stock | Size: 2.75 | Shape: Round | Sterility: | Packaging: 4 electrodes per pack (4 electrodes total) | Price: $6.71 | variation_pricing_suffix: pack |
Incorporates a silver ink/carbon film conductive layer, proven to efficiently disperse electrical current over the entire surface of the electrode. Features an intuitive life tab for easy removal of the electrode after application. The hydrogel is formulated with pure aloe vera, known for its hydrating properties and natural moisturizing effects. A tinted double-coated liner makes storage easy as electrodes can be returned to either side. Multiple applications from 10-15 days.
| Weight | 0.1000 lbs |
|---|---|
| Dimensions | 10 × 10 × 10 in |
| Size | 2×2, 4×2, 2, 2.75, 2×4, 1.6×1.75 |
| Shape | Square, Rectangle, Round, Oval |
| Material | Silver Ink/Carbon Film |
| Sterility | Non-Sterile |
| Packaging | 4 electrodes per pack (4 electrodes total), 1 pack per case (1 pack total), 40 electrodes per pack, 10 packs per case (400 electrodes total) |
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Semaglutide API Product Description:
COA Available Product with NDC Code
Available in the US and Canada.
Semaglutide API is indicated for improving glycemic control in adults with type 2 diabetes mellitus, in conjunction with diet and exercise. The approved therapeutic doses are 0.5 mg and 1 mg. Type 2 diabetes is a chronic metabolic disorder characterized by high blood sugar, insulin resistance, and insufficient insulin production. The onset of this condition is linked to the inability of beta cells to respond to increased plasma glucose, predominantly caused by lifestyle factors such as overweight and obesity. The key feature of type 2 diabetes is insulin resistance, which reduces insulin’s effectiveness at normal concentrations. Insulin secretion is stimulated by incretins like glucagon-like peptide 1 (GLP-1), which also delays gastric emptying and induces satiety.
Mode of Action:
Semaglutide API enhances glucose control through various mechanisms, including increased insulin secretion, slower gastric emptying, and reduced postprandial glucagon and food intake. The drug mimics the activity of GLP-1, a key hormone in glucose management, thanks to structural modifications that improve its stability against degradation by enzymes like dipeptidyl peptidase-4 (DPP-4). These modifications also promote specific binding to plasma albumin and prevent incorrect binding of fatty acids, resulting in an extended half-life and improved patient compliance.
Pharmacodynamics:
Clinical trials show that semaglutide significantly reduces glycated hemoglobin (HbA1c) compared to other medications, including sitagliptin, exenatide, and insulin glargine U100. HbA1c is a standard measure of high glucose levels, reflecting long-term blood sugar control. Additionally, semaglutide has been shown to reduce body weight, lower fasting and postprandial glucose levels, and decrease fasting triglycerides and VLDL cholesterol.
Metabolism:
Semaglutide is slowly but extensively metabolized before excretion, with 83% of the administered dose found unchanged in plasma. Six different metabolites have been identified, with the major metabolite accounting for 7.7% of the dose. The drug is primarily degraded by enzymes such as DPP-4 and neural endopeptidase (NEP), which inactivate semaglutide and hydrolyze its peptide bonds.
Toxicity:
In preclinical studies, mild c-cell hyperplasia and other effects, including liver necrosis and centrilobular hypertrophy, were observed at doses significantly higher than those used clinically. High doses also resulted in ECG abnormalities and tissue vacuolation.
IUPAC:
17-{[(1R)-3-[(2-{2-[({2-[2-({[(5S)-5-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S,3R)-2-{2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-2-methylpropanamido}-4-carboxybutanamido]acetamido}-3-hydroxybutanamido]-3-phenylpropanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]-3-carboxypropanamido]-3-methylbutanamido]-3-hydroxypropanamido]-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-carboxybutanamido]acetamido}-4-carbamoylbutanamido]propanamido]propanamido]-5-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-[({[(1S)-4-carbamimidamido-1-[(carboxymethyl)carbamoyl]butyl]carbamoyl}methyl)carbamoyl]butyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-phenylethyl]carbamoyl}-3-carboxypropyl]carbamoyl}pentyl]carbamoyl}methoxy)ethoxy]ethyl}carbamoyl)methoxy]ethoxy}ethyl)carbamoyl]-1-carboxypropyl]carbamoyl}heptadecanoic acid
DrugBank:
DB13928
Formula:
C187-H291-N45-O59
Molecular Mass:
Average: 4113.641
Monoisotopic: 4111.11537713
Synonyms:
Semaglutide / Semaglutide API
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](NC(=O)CCCCCCCCCCCCCCCCC(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)C(C)(C)NC(=O)[C@@H](N)CC1=CNC=N1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O
InChi:
InChI=1S/C187H291N45O59/c1-18-105(10)154(180(282)208-108(13)159(261)216-133(86-114-89-200-119-50-40-39-49-117(114)119)170(272)218-129(82-102(4)5)171(273)228-152(103(6)7)178(280)215-121(53-44-72-199-186(192)193)162(264)201-91-141(242)209-120(52-43-71-198-185(190)191)161(263)204-94-151(257)258)230-172(274)131(83-111-45-33-31-34-46-111)219-167(269)126(64-69-149(253)254)214-166(268)122(51-41-42-70-195-144(245)98-290-79-78-289-76-74-197-145(246)99-291-80-77-288-75-73-196-139(240)66-61-127(183(285)286)211-140(241)54-37-29-27-25-23-21-19-20-22-24-26-28-30-38-55-146(247)248)212-158(260)107(12)206-157(259)106(11)207-165(267)125(60-65-138(189)239)210-142(243)92-202-163(265)123(62-67-147(249)250)213-168(270)128(81-101(2)3)217-169(271)130(85-113-56-58-116(238)59-57-113)220-175(277)135(95-233)223-177(279)137(97-235)224-179(281)153(104(8)9)229-174(276)134(88-150(255)256)221-176(278)136(96-234)225-182(284)156(110(15)237)231-173(275)132(84-112-47-35-32-36-48-112)222-181(283)155(109(14)236)227-143(244)93-203-164(266)124(63-68-148(251)252)226-184(287)187(16,17)232-160(262)118(188)87-115-90-194-100-205-115/h31-36,39-40,45-50,56-59,89-90,100-110,118,120-137,152-156,200,233-238H,18-30,37-38,41-44,51-55,60-88,91-99,188H2,1-17H3,(H2,189,239)(H,194,205)(H,195,245)(H,196,240)(H,197,246)(H,201,264)(H,202,265)(H,203,266)(H,204,263)(H,206,259)(H,207,267)(H,208,282)(H,209,242)(H,210,243)(H,211,241)(H,212,260)(H,213,270)(H,214,268)(H,215,280)(H,216,261)(H,217,271)(H,218,272)(H,219,269)(H,220,277)(H,221,278)(H,222,283)(H,223,279)(H,224,281)(H,225,284)(H,226,287)(H,227,244)(H,228,273)(H,229,276)(H,230,274)(H,231,275)(H,232,262)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,285,286)(H4,190,191,198)(H4,192,193,199)/t105-,106-,107-,108-,109 ,110 ,118-,120-,121-,122-,123-,124-,125-,126-,127 ,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,152-,153-,154-,155-,156-/m0/s1
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Lysol On-The-Go Citrus Disinfectant Wipes are your perfect companion for maintaining hygiene wherever you are. Packaged in a convenient 15-wipe count, these wipes are designed for easy transport and use on the move. With the power to kill 99.99% of viruses and bacteria, including those responsible for cold and flu, these wipes are an essential item for your hygiene kit.
Product Features:
- Powerful Disinfectant: Lysol On-The-Go Kills 99.99% of viruses and bacteria, including 8 cold and flu viruses, Salmonella, E. Coli, MRSA, Staph, and Strep viruses, along with antibiotic-resistant bacteria.
- Allergen Removal: Effectively removes more than 95% of allergens, making it ideal for users sensitive to common allergens.
- Unique Micro-Pocket Pattern: Designed to trap and lift everyday messes quickly, making cleaning up spills and dirt a breeze.
- Safe on Electronics: Can be safely used on electronics, including smartphones, tablets, and remote controls, without damaging the devices.
- Citrus Scent: Leaves a fresh and invigorating citrus fragrance after cleaning, refreshing any space instantly.
Specifications:
- Unit Quantity: 24 packs per case, 15 wipes per pack
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- Packaging Dimensions: The case measures 12 inches in length, 9.64 inches in width, and 7.52 inches in height.
- Shelf Life: 24 months, guaranteeing long-lasting effectiveness.
Usage: Ideal for quick clean-ups and disinfecting surfaces while traveling, at work, or in public spaces. Perfect for cleaning hard, non-porous surfaces, offering peace of mind by reducing the risk of infection.
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- Lysol On-The-Go comes in a case of 24 packs, each containing 15 wipes, with easy-to-open packaging that fits into any bag or glove compartment, making it perfect for on-the-go use.
Lysol On-The-Go Citrus Disinfectant Wipes provide the trusted disinfecting power of Lysol in a compact, travel-friendly package. Whether you’re commuting, traveling, or simply out and about, these wipes offer a quick and convenient way to ensure the surfaces you come into contact with are sanitized, keeping you and your loved ones protected from germs and bacteria.
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