KINESIO MEDICAL TAPING FOR THE MATURE ADULT
$52.65 / each
Kinesio® Medical Taping for the Mature Adult is a hands-on book designed for general use; it is intended for older active adults and their families, and also includes helpful applications for caregivers and their patients.
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Kinesio® Medical Taping for the Mature Adult is a hands-on book designed for general use; it is intended for older active adults and their families, and also includes helpful applications for caregivers and their patients.
| Weight | 1.3000 lbs |
|---|---|
| Dimensions | 10 × 10 × 10 in |
| Color | Green |
| Width | 2" |
| Length | 16.4' |
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Semaglutide API Product Description:
COA Available Product with NDC Code
Available in the US and Canada.
Semaglutide API is indicated for improving glycemic control in adults with type 2 diabetes mellitus, in conjunction with diet and exercise. The approved therapeutic doses are 0.5 mg and 1 mg. Type 2 diabetes is a chronic metabolic disorder characterized by high blood sugar, insulin resistance, and insufficient insulin production. The onset of this condition is linked to the inability of beta cells to respond to increased plasma glucose, predominantly caused by lifestyle factors such as overweight and obesity. The key feature of type 2 diabetes is insulin resistance, which reduces insulin’s effectiveness at normal concentrations. Insulin secretion is stimulated by incretins like glucagon-like peptide 1 (GLP-1), which also delays gastric emptying and induces satiety.
Mode of Action:
Semaglutide API enhances glucose control through various mechanisms, including increased insulin secretion, slower gastric emptying, and reduced postprandial glucagon and food intake. The drug mimics the activity of GLP-1, a key hormone in glucose management, thanks to structural modifications that improve its stability against degradation by enzymes like dipeptidyl peptidase-4 (DPP-4). These modifications also promote specific binding to plasma albumin and prevent incorrect binding of fatty acids, resulting in an extended half-life and improved patient compliance.
Pharmacodynamics:
Clinical trials show that semaglutide significantly reduces glycated hemoglobin (HbA1c) compared to other medications, including sitagliptin, exenatide, and insulin glargine U100. HbA1c is a standard measure of high glucose levels, reflecting long-term blood sugar control. Additionally, semaglutide has been shown to reduce body weight, lower fasting and postprandial glucose levels, and decrease fasting triglycerides and VLDL cholesterol.
Metabolism:
Semaglutide is slowly but extensively metabolized before excretion, with 83% of the administered dose found unchanged in plasma. Six different metabolites have been identified, with the major metabolite accounting for 7.7% of the dose. The drug is primarily degraded by enzymes such as DPP-4 and neural endopeptidase (NEP), which inactivate semaglutide and hydrolyze its peptide bonds.
Toxicity:
In preclinical studies, mild c-cell hyperplasia and other effects, including liver necrosis and centrilobular hypertrophy, were observed at doses significantly higher than those used clinically. High doses also resulted in ECG abnormalities and tissue vacuolation.
IUPAC:
17-{[(1R)-3-[(2-{2-[({2-[2-({[(5S)-5-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S,3R)-2-{2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-2-methylpropanamido}-4-carboxybutanamido]acetamido}-3-hydroxybutanamido]-3-phenylpropanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]-3-carboxypropanamido]-3-methylbutanamido]-3-hydroxypropanamido]-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-carboxybutanamido]acetamido}-4-carbamoylbutanamido]propanamido]propanamido]-5-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-[({[(1S)-4-carbamimidamido-1-[(carboxymethyl)carbamoyl]butyl]carbamoyl}methyl)carbamoyl]butyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}ethyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-phenylethyl]carbamoyl}-3-carboxypropyl]carbamoyl}pentyl]carbamoyl}methoxy)ethoxy]ethyl}carbamoyl)methoxy]ethoxy}ethyl)carbamoyl]-1-carboxypropyl]carbamoyl}heptadecanoic acid
DrugBank:
DB13928
Formula:
C187-H291-N45-O59
Molecular Mass:
Average: 4113.641
Monoisotopic: 4111.11537713
Synonyms:
Semaglutide / Semaglutide API
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](NC(=O)CCCCCCCCCCCCCCCCC(O)=O)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)C(C)(C)NC(=O)[C@@H](N)CC1=CNC=N1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O
InChi:
InChI=1S/C187H291N45O59/c1-18-105(10)154(180(282)208-108(13)159(261)216-133(86-114-89-200-119-50-40-39-49-117(114)119)170(272)218-129(82-102(4)5)171(273)228-152(103(6)7)178(280)215-121(53-44-72-199-186(192)193)162(264)201-91-141(242)209-120(52-43-71-198-185(190)191)161(263)204-94-151(257)258)230-172(274)131(83-111-45-33-31-34-46-111)219-167(269)126(64-69-149(253)254)214-166(268)122(51-41-42-70-195-144(245)98-290-79-78-289-76-74-197-145(246)99-291-80-77-288-75-73-196-139(240)66-61-127(183(285)286)211-140(241)54-37-29-27-25-23-21-19-20-22-24-26-28-30-38-55-146(247)248)212-158(260)107(12)206-157(259)106(11)207-165(267)125(60-65-138(189)239)210-142(243)92-202-163(265)123(62-67-147(249)250)213-168(270)128(81-101(2)3)217-169(271)130(85-113-56-58-116(238)59-57-113)220-175(277)135(95-233)223-177(279)137(97-235)224-179(281)153(104(8)9)229-174(276)134(88-150(255)256)221-176(278)136(96-234)225-182(284)156(110(15)237)231-173(275)132(84-112-47-35-32-36-48-112)222-181(283)155(109(14)236)227-143(244)93-203-164(266)124(63-68-148(251)252)226-184(287)187(16,17)232-160(262)118(188)87-115-90-194-100-205-115/h31-36,39-40,45-50,56-59,89-90,100-110,118,120-137,152-156,200,233-238H,18-30,37-38,41-44,51-55,60-88,91-99,188H2,1-17H3,(H2,189,239)(H,194,205)(H,195,245)(H,196,240)(H,197,246)(H,201,264)(H,202,265)(H,203,266)(H,204,263)(H,206,259)(H,207,267)(H,208,282)(H,209,242)(H,210,243)(H,211,241)(H,212,260)(H,213,270)(H,214,268)(H,215,280)(H,216,261)(H,217,271)(H,218,272)(H,219,269)(H,220,277)(H,221,278)(H,222,283)(H,223,279)(H,224,281)(H,225,284)(H,226,287)(H,227,244)(H,228,273)(H,229,276)(H,230,274)(H,231,275)(H,232,262)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,285,286)(H4,190,191,198)(H4,192,193,199)/t105-,106-,107-,108-,109 ,110 ,118-,120-,121-,122-,123-,124-,125-,126-,127 ,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,152-,153-,154-,155-,156-/m0/s1
Purchase of this product is restricted to licensed companies and labs.
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Ideal for cast support, injuries to the arm, wrist or hand.
- Comfortable.
- Web shoulder strap.
- Slide buckle closure.
Additional Information:
- Feature / Property: Web Strap, Slide Buckle Closure, for Cast Support/Injuries to Arm/Wrist/Hand
- Depth: 8.5″
- Length: 22.5″
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Disposable / Reusable: Disposable
Colour: Blue
Length: 5″
e.FORCEPS PLASTIC DISP 5IN BLUE AUTOCLAVABLE 50EA/PK 30PK/CA
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SPECULUM VAGINAL GRAVES MED 1EA
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Features & Benefits
Product Specs
Acetaminophen Injection is a sterile, clear, colorless, nonpyrogenic, isotonic formulation of acetaminophen intended for intravenous infusion
Acetaminophen is a nonsalicylate antipyretic and nonopioid analgesic agent; chemical name is N-acetyl-p-aminophenol
PAB IV bags not made with PVC or DEHP
Easy to spike port
Linear bar code
24/CS
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Individually checked with maximum precision for perfect workmanship, pattern, and finish.
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ProActive Self Adhesive Electrode is a versatile and reusable electrode that can be used with most TENS and muscle electro stimulators. With a built-in conductive gel surface that remains effective for up to 30 uses,ProActive Self Adhesive Electrode is pre-wired and pre-gelled for easy and convenient application. The flexible cloth backing allows the electrode to conform to all body surfaces, while the rounded edges prevent electrode curl-up. The hypo-allergenic gel keeps the skin soft and the anchored pigtail prevents wire pull-out, increasing the usage life. Available in a variety of shapes and sizes, these latex-free electrodes are perfect for multiple treatment zones.
Self-adhesive, pre-gelled & reusable Electrodes for use with most TENS and muscle electro stimulators
- Built-in conductive gel surface remains effective for up to 30 uses
- Flexible cloth backing allows the electrode to easily and durably conform to all body surfaces
- Pre-wired and pre-gelled for easy and convenient application
- Long lasting, hypo-allergenic gel keeps skin soft
- Rounded edges for prevention of electrode curl-up
- Anchored pigtail prevents wire pull-out and increases usage life
- Available in a variety of shapes and sizes for application to multiple treatment zones
- Latex-Free
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Detecto 349 Mechanical Physician Scale with Height Rod and Handpost, 440 lb x 4 oz
The Detecto name is globally recognized as one of the leading manufacturers of dependable mechanical healthcare scales. Durability and trust is proven with their products being backed by a manufactures warranty of two years. The 349 series can be found in your general doctor’s office all the way to cutting-edge medical research facilities. It includes a built-in height measuring rod, and stability handpost, and is capable of weighing in metric and standard. A nonslip weighing platter offers safety and security for patients young and old.
Features
- Capable of weighing in lb or kg
- The capacity of 440 lb with a 4 oz readability or capacity of 200 kg with a 100 g readability
- No power is required!
- Sturdy steel construction with a powder-coated paint finish
- Built-in height measuring rod
- Mounted handpost to help stabilize patients
- Simple to operate balance and slide
- Slip-resistant top plate for security
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Individually checked under rigid quality controlled conditions. Hand crafted, in some cases there may be minor variations of the indicated measurements.
- Graduated in cm.
- Malleable.
- Material: Stainless Steel.
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Lysol On-The-Go Citrus Disinfectant Wipes are your perfect companion for maintaining hygiene wherever you are. Packaged in a convenient 15-wipe count, these wipes are designed for easy transport and use on the move. With the power to kill 99.99% of viruses and bacteria, including those responsible for cold and flu, these wipes are an essential item for your hygiene kit.
Product Features:
- Powerful Disinfectant: Lysol On-The-Go Kills 99.99% of viruses and bacteria, including 8 cold and flu viruses, Salmonella, E. Coli, MRSA, Staph, and Strep viruses, along with antibiotic-resistant bacteria.
- Allergen Removal: Effectively removes more than 95% of allergens, making it ideal for users sensitive to common allergens.
- Unique Micro-Pocket Pattern: Designed to trap and lift everyday messes quickly, making cleaning up spills and dirt a breeze.
- Safe on Electronics: Can be safely used on electronics, including smartphones, tablets, and remote controls, without damaging the devices.
- Citrus Scent: Leaves a fresh and invigorating citrus fragrance after cleaning, refreshing any space instantly.
Specifications:
- Unit Quantity: 24 packs per case, 15 wipes per pack
- Product Size: Each wipe is ready-to-use (RTU), ensuring immediate disinfection and cleaning.
- Packaging Dimensions: The case measures 12 inches in length, 9.64 inches in width, and 7.52 inches in height.
- Shelf Life: 24 months, guaranteeing long-lasting effectiveness.
Usage: Ideal for quick clean-ups and disinfecting surfaces while traveling, at work, or in public spaces. Perfect for cleaning hard, non-porous surfaces, offering peace of mind by reducing the risk of infection.
Packaging:
- Lysol On-The-Go comes in a case of 24 packs, each containing 15 wipes, with easy-to-open packaging that fits into any bag or glove compartment, making it perfect for on-the-go use.
Lysol On-The-Go Citrus Disinfectant Wipes provide the trusted disinfecting power of Lysol in a compact, travel-friendly package. Whether you’re commuting, traveling, or simply out and about, these wipes offer a quick and convenient way to ensure the surfaces you come into contact with are sanitized, keeping you and your loved ones protected from germs and bacteria.
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